Diamond Princess II

Design of the PRINCESS trial: pre-hospital resuscitation intra-nasal cooling effectiveness survival study (PRINCESS)

BACKGROUND Therapeutic hypothermia (TH, 32-34°C) has been shown to improve neurological outcome in comatose survivors of out-of-hospital cardiac arrest (OHCA) with ventricular tachycardia or fibrillation. Earlier initiation of TH may increase the beneficial effects. Experimental studies have suggested that starting TH during cardiopulmonary resuscitation (CPR) may further enhance its neuroprote...

The Princess Margaret Hospital, Swindon.

Winning the Hand of the Princess Saralinda

Suitors come to the castle in order to try to win the hand of the Princess Saralinda. The first suitor to perform n amazing feats will succeed. If the number n of feats is large and the times to perform the feats are all i.i.d., then how long is it before a suitor will win the hand of the Princess? We develop asymptotics describing the distribution of this random time as the number of feats get...

Spongy Diamond

Rhombellanes are mathematical structures existing in various environments, in crystal or quasicrystal networks, or even in their homeomorphs, further possible becoming real molecules. Rhombellanes originate in the K2.3 complete bipartite graph, a tile found in the linear polymeric staffanes. In close analogy, a rod-like polymer derived from hexahydroxy-cyclohexane was imagined. Further, the ide...

Princess Margaret Cancer Centre Clinical Practice Guidelines